Asklemmy

42525 readers

1401 users here now

A loosely moderated place to ask open-ended questions

Search asklemmy 🔍

If your post meets the following criteria, it's welcome here!

Open-ended question
Not offensive: at this point, we do not have the bandwidth to moderate overtly political discussions. Assume best intent and be excellent to each other.
Not regarding using or support for Lemmy: context, see the list of support communities and tools for finding communities below
Not ad nauseam inducing: please make sure it is a question that would be new to most members
An actual topic of discussion

Looking for support?

Looking for a community?

Lemmyverse: community search
sub.rehab: maps old subreddits to fediverse options, marks official as such
[email protected]: a community for finding communities

~Icon~ ~by~ ~@Double_[email protected]~

founded 5 years ago

MODERATORS

[email protected]

Did anyone have any positive results with CBD products? (feddit.de)

submitted 11 months ago by [email protected] to c/[email protected]

116 comments fedilink hide all child comments

Not too long ago, regulations on CBD changed in Germany leading to a plethora of products containing it. As someone who occasionally needs pain medication, I tried some of the products to avoid regular pain killers (ibu). Especially on days with lighter pain, I wished for an alternative to the sledgehammer meds. But I was left standing in the rain. I didn't feel any effect. That's why I would love to hear from your experiments and experience.

you are viewing a single comment's thread
view the rest of the comments

[–] [email protected] 8 points 11 months ago* (last edited 11 months ago) (5 children)

I'm having trouble finding it, but I ran across a study a few months ago whose results pointed to greater pain relief gains when CBD was consumed with THC, and that both substances alone do less to "relieve" pain.

I wouldn't say it helps relieve pain as much as it lets you be distracted from pain.

Also, personally, when I have used CBD on it's own, it never did anything for me at all. It only ever worked in combination with THC.

Finally, people taking other medications need to be careful about taking CBD.

The vast majority of medications are broken down by enzyme CYP3A4, an enzyme that CBD inhibits.

I am taking a life-saving/life-altering medication to manage a severe disease. It is handled in my body by CYP3A4. Meaning I can really fuck up my medication dosage by taking CBD on its own, because it will inhibit the ability of CYP3A4 to ingest the drug.

User [email protected] helpfully pointed out that grapefruit inhibits CYP3A4 as well, so if you're not supposed to eat grapefruit, you should probably also avoid CBD. I hadn't even made that connection myself, very astute, pizza_rolls!

[–] [email protected] 2 points 11 months ago (1 children)

I used to take CBD every day for anxiety and I only found this out after a couple years so thanks for bringing it up. If your medication says to avoid grapefruit, then you probably should not take CBD

[–] [email protected] 1 points 11 months ago

If your medication says to avoid grapefruit, then you probably should not take CBD

I didn't even make that connection, but yeah, exactly! Grapefruit inhibits the exact same enzyme. That's a really good way to know, I'm going to add that to my post.

load more comments (3 replies)