[-] [email protected] 34 points 1 month ago

So this is neat. Potentially life changing for some type 2 diabetics, but that depends because some t2 diabetics are not failing to make enough insulin, they're just no longer sensitive to it at a level that makes it functional for them. I suppose it's possible that this therapy could cause them to grow enough islet β cells to overcome their lack of sensitivity, but (and I'm a type 1, not a type 2, so maybe my info is incorrect here) that lack of sensitivity can grow with further exposure to insulin making this a stop-gap at best for those cases absent other therapies.

...and with all of that said, being able to regrow islet β cells has never really been the problem for type 1 diabetes. You can regrow all the islet β cells you'd like and it's not going to cure the underlying immune disease that has caused your immune system to kill off all of your islet β cells to begin with. Unless you can figure out why t1 diabetes causes one's own immune system to go psycho killer on their islet β cells, you've done nothing to "cure" diabetes. Without being able to suppress that impulse for your immune system to murder your own cells, any ability to replace the islet β cells is going to be temporary at best, and probably a waste on the whole.

My brother in law is a "cured" type 1 diabetic, by virtue of his having had a kidney replacement and being on immune suppressing drugs for that. Since they were already replacing the kidney and he was going to have to take immune system suppression medications for that, they also just replaced his pancreas at the same time and the suppression of his immune system has allowed the new pancreas to thrive and continue to make insulin. Easy-peasy. The only trade-off is that he is super immunocompromised and can be killed by common colds, so not a great strategy in general.

[-] [email protected] 2 points 1 month ago

Attributes only apply to the directory’s own allocation table and child directories have their own tables.

Thanks. It has been a while, but I was fairly certain that this was the case, glad to have the confirmation. 👍

[-] [email protected] 6 points 1 month ago* (last edited 1 month ago)

If you'd like to look into it further. the +i flag in chattr is setting an attribute making the file (everything in Linux is a file, so yes this even means directories) immutable. When a file is immutable, it isn't possible to change the ownership, group, name, or permissions of the file, nor will you be able to write, append, or truncate the file.

It's been a while since I've used it, but I don't believe it's possible to have an immutable directory where you can still modify the contents therein, but I may be misremembering that. It would seem unlikely since adding content to the directory should require that you modify the links for the directory, which shouldn't be allowable with an immutable object?

It's possible that the +a chattr attribute may achieve what you'd prefer. I believe that flag will make it so that files (and again, everything in Linux is a file) can be created and modified, but never deleted. I've actually never used this one, but I can foresee how this still may not be ideal for your wishes since updates to games may expect to be able to delete old content which would be thwarted here. 🤷

[-] [email protected] 5 points 1 month ago

I accidentally misclicked this article and reported it as spam while I was trying to report some prescription drug spam. Hopefully it's not adversely affected. I wish there was an Undo on that action.

[-] [email protected] 6 points 1 month ago

The Nissan Connect stuff doesn't work anymore for any of the 2016 Leafs, they used a form of cell service that is no longer in operation.

I swapped a nice Kenwood head unit into my Leaf for a couple hundred dollars. It maintains the backup camera, steering wheel controls, and the built in USB port while offering a larger screen and touch screen controls for Android Auto or Apple Car Play if you want them. It's awesome and I highly recommend it for anyone who wants a short range commuter car.

[-] [email protected] 2 points 1 month ago

I'm now deeply curious if it works for your use case. Hit me back if you give it a go and let me know if it works out or not.

[-] [email protected] 18 points 1 month ago

If gaming with Nvidia hardware is your primary concern, then maybe Bazzite would suit you. It's based on Immutable Fedora, with tweaks to give it a SteamOS like experience. It offers Gnome or KDE for the desktop, and supposedly has everything dialed in for gaming. I've heard a bunch about it doing great with Nvidia cards and gaming in general, I suspect that you'd be able to do everything else you might need via the desktop it provides, but I have no knowledge of how it handles multiple monitors so maybe therein lies the fatal flaw.

[-] [email protected] 3 points 1 month ago* (last edited 1 month ago)

I assume this is a Stargate thing and that there aren't actually that many Skeptical Guide podcasts out there.

I haven't got any dog in the Stargate fight, I've seen the original movie (good) and watched the Richard Dean Anderson TV series (better than the movie) for a while before it just fell off my radar? I'll take your word for it that Stargate Universe is the lesser of the Stargate properties.

SGU in my comment obviously is referring to the Skeptics Guide to the Universe aka, the linked podcast.

[-] [email protected] 4 points 1 month ago* (last edited 1 month ago)

If you use a fancy official VPN client from Mullvad, PIA, etc, you won’t need this since most clients already have a kill switch built in (also called Lockdown Mode in Mullvad).

According to the researchers...

The result of this is the user transmits packets that are never encrypted by a VPN, and an attacker can snoop their traffic. We are using the term decloaking to refer to this effect. Importantly, the VPN control channel is maintained so features such as kill switches are never tripped, and users continue to show as connected to a VPN in all the cases we’ve observed.

Killswitches are insufficient protection since the TunnelVision attack never disables the VPN tunnel. The TunnelVision attackers are instructing your physical layer connection to route everything through a node of their choosing rather than killing your VPN connection, and since the VPN connection never drops, a killswitch will never engage. The VPN stays up, thinking it is doing a good job, but in the meantime your network interface has been instructed to route no traffic through the VPN and instead route everything to the location of the attacker's choosing. I have heard that a couple of VPNs think their clients are not vulnerable here, but I haven't seen independent conclusive proof one way or the other yet.

I suspect that your "Solution" also fails to mitigate the issues in TunnelVision because it allows LAN access to the physical interface. In a TunnelVision attack the hostile has to be on your LAN (or rather the same LAN you are on since I suspect that "The coffee shop wi-fi" is the more likely network for an attack like this) already, so if they're going to tell your interface to route traffic somewhere else, in all likelihood that somewhere else will already be in the same LAN you are and their exfiltration will be allowed under your configuration.

[-] [email protected] 3 points 1 month ago

I've never listened to Rogan*, but I think https://www.theskepticsguide.org/podcasts does an excellent job of talking about current news and science items in an easily digestible format that mostly avoids bullshit while probably filling the same gee-whiz niche that people expect from Rogan? It's a panel, so not a single muscular male host, but I think if your sibling is pursuing Rogan because they think it's helping expose them to new interesting ideas, SGU is a vastly superior route to that end.


*I actually think my only Rogan exposure has been the SGU talking about how he more or less just believes the last thing anyone told him, whatever that might be, which seems... less good?

[-] [email protected] 5 points 2 months ago

https://www.patreon.com/Orioto

Might just be a me thing, but this guy puts out a new wallpaper almost every week and they're all amazing. The higher tiers allow you to participate in choosing the next wallpaper, but they're mostly for 1080p, 1440p, and 2160p. Buying in once gets you the whole lot of everything he's done until now.

[-] [email protected] 1 points 2 months ago

Bluetooth headphones are not modernity, they should of course be an option, but increasingly they are the only game in town. Wired is still king for loads of things, not the least of which is reliability.

You wanna know how many times my wired Sennheiser's have been unable to put music in my ear holes? Never. They always work. Care to guess how many wireless headphones have been able to provide sound every time I've wanted it without delay or failure? None. I've owned more than 2 dozen wireless this, that, and the other, headphones & earbuds, and none of them have been even a shadow of the reliability offered by my old wired headphones. Which is to say nothing of the fact that the wired experience usually sounds better (Still don't think you can get any comfortable phat 600ohm monster cans that don't have a wire) and has no issues with making sound when you're in a space that is saturating the 2.4Ghz band (my Costco is usually so full of idiots on Bluetooth that you can't get a reliable experience for anything from any wireless audio device.)

You seem to think it's "backwards rhetoric" to want a feature that will never be offered in a wireless setup, and that's just fucked man. There are a wealth of reasons why wireless does not fully replace wired. It's why anything that doesn't have to move generally gets a fixed connection, it's just more reliable and often more efficient. That's not backwards, it's just a priority that you don't value above others. If landlines or floppy disks offered any advantages over anything else they'd still be around today (and arguably they are in some limited niches,) but the replacements for those technologies have had no downsides against their replacements while wireless tech still has some significant downsides (again, maybe you don't weight the pros and cons the same, so this may not apply to you) against the technology they are meant to replace, and will likely never see 100% capture of their role as a result.

TL;DR: Stop trying to frame this as some sort of crusade against the future, there are legit cases where wired is just better than wireless.

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DarthYoshiBoy

joined 1 year ago