This is kinda the opposite of what you're asking for, but might address the reason that you're asking the question?
CachyOS is an Arch based distro, but it precompiles many arch packages (and some AUR packages) in several versions, optimised for either x86_64-v3 or x86_64-v4.
So if your goal is "optimised" rather than "compile yourself" it might be worth looking at
The joys of being a 2E student.
Gifted, with undiagnosed ADHD.
Flew in to university without ever learning how to organise my time. Smashed every exam university put in front of me. Failed every form of written assessment that required time management and planning, instead of just knowing the answers. Even after they put me on academic probation and I understood how serious it was, I couldn't fix it, because I didn't know I had ADHD at the time, and had never learned the organisational skills required, because I'd never needed them to succeed academically before.